Ronald Grisanti D.C., D.A.B.C.O., D.A.C.B.N., M.S., CFMP
Read the labels on the foods you buy. Watch out for the ingredient carrageenan. Carrageenan is considered a harmless food additive by the US government. Unfortunately medical research has proven otherwise. Carrageenan is known as Irish Moss and is actually a seaweed. Most people would assume that this food additive would be nutritious considering it is a sea vegetable. On a positive note this sea vegetable is high in iodine, sulfur, trace minerals and vitamins. But it is important to know that the bad far outweighs the good when it comes to the consumption of carrageenan. In over 40 studies, carrageenan was found to create ulcers and cancers in animals. It easily triggers inflammatory disease in the human colon as well. And many researchers believe that it promotes not only irritable bowel but breast cancers and more. It changes detoxification in sulfur pathways (needed for hormones, toxins, etc.,), and may even be responsible for DVT (deep vein thromboses or blood clots in the lower legs). Chemists have discovered that carrageenan suppresses gamma interferon, a cytokine crucial for tumor and infectious control (like hepatitis), as well as control of inflammation and autoimmune disease, arthritis, and more. Finally carrageenan has been found to be part of the cause of the epidemic of diabetes, insulin resistance, metabolic syndrome, and more. The average intake of carrageenan for most individuals is 100 mg a day. Where do you find carrageenan? It prevents separation in foods containing milk or chocolate, and improves the texture of not only foods, but cosmetics and even toothpastes, room deodorizers and pesticides. It's commonly found in cottage cheese and ice cream to infant formulas, dietetic beverages and low-fat meats and yogurts. For decades it was used as a thickener in puddings. So the take-away is read the labels on the foods and products you consume and stay clear of anything that has carrageenan listed. To find a healthcare professional certified in functional medicine, go to www.FunctionalMedicineDoctors.com.These are clinicians who have been trained at Functional Medicine University (www.FunctionalMedicineUniversity.com) References: Tobacman JK, et al, Review of harmful gastrointestinal effects of carrageenan in animal studies, Environ Health Persp 109; 10, 2001 Tobacman JK, et al, Carrageenan induces interleukin-8 production through distinct Bc110 pathway in normal human colonic epithelial cells, Am J Physiol, 292: G829, 2006 Suzuki F, et al, Suppression of interferon gamma production in mice treated with carrageenan, Eur J Immunol 16; 4:375-80, 1986 Thompson AW, et al. Immunopharmacology of the macrophagetoxic agent carrageenan, Int J Immunol Pharmacol 1:247-61, 1979 Bhattachryya S, et al, Exposure to the common food additive carrageenan leads to glucose intolerance, insulin resistance, inhibition of insulin signaling…, Diabetologia 55; 1:194-203, 2012 Tomioka H, et al, Comparative roles of macrophages and NK cells in the host resistance of mice to Mycobacterium fortuitum infection, J Infect 48:74-80, 2004 (In this study the investigators found that 3 out of 4 infected mice given carrageenan died of infection) McKim JM, et al, Food additive carrageenan Part I: A critical review of carrageenan in vitro studies, potential pitfalls and implications for human health and safety, Crit Rev Toxicol 44; 3:211-43, 2014 Yang B, et al, Exposure to common food additive carrageenan leads to reduced sulfatase activity…,Biochimie 94; 6:1309-16, 2012 (and it changes heparin-heparan sulfate disaccharides; does this mean it could lead to deep vein thromboses and lung clots?) Duarte DB, et al, Models of inflammation: Carrageenan air pouch, Current Protocols Pharmacology, chap 5, unit 5, 6, 2012 (PMID 2278300, carrageenan is used to create inflammation to study NSAIDs) Gong D, et al, Phytother Res 26; 3:397-402, 2012 (carrageenan is used to create arthritis for animal studies The information on this website is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge and information from the research and experience of Dr. Grisanti and his functional medicine community. Dr. Grisanti encourages you to make your own health care decisions based upon your research and in partnership with a qualified health care professional. Visit www.FunctionalMedicineUniversity.com for more information on our training in functional medicine.
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Ronald Grisanti D.C., D.A.B.C.O., D.A.C.B.N., M.S.,CFMP
There is now a new natural weapon to combat against the growing population of high blood pressure sufferers. Now this new weapon is as close as your backyard. What I am talking about is good old sunlight. Blood pressure levels are commonly higher during winter months. The question you may ask is what is the mechanism that allows sunlight to lower blood pressure? British researchers have figured out why. The answer is nitric oxide (NO). Nitric oxide is known to reduce blood pressure by evoking vasodilation either directly by causing relaxation of vascular smooth muscle or indirectly by acting in the rostral brainstem to reduce central sympathetic outflow, which decreases the release of norepinephrine from sympathetic nerve terminals. Basically, nitric oxide increases the elasticity of the artery walls and helps to normalize high blood pressure. An increasingly large body of literature suggests that alterations in the NO system may play an important role in the development or maintenance of clinical hypertension. What they found is that nitric oxide stored in the top layers of the skin reacts to sunlight and causes blood vessels to widen as the oxide moves into the bloodstream. That, in turn, lowers blood pressure. According to researcher Martin Feelisch, a professor of experimental medicine and integrative biology at the University of Southampton, exposure to ultraviolet light might help reduce the risk for heart disease. "This new study finds that UV light exposure to the skin induced nitric oxide release and modestly lowered blood pressure, suggesting that this may play a role in modulating blood pressure," said Fonarow, a spokesman for the American Heart Association. In 2009, a team led by the University of Edinburgh's Richard Weller showed that human skin and the dermal vasculature contain significant stores of NO—much more than can be found circulating in the blood—and that these stores could be mobilized by UVA (long-wave UV) irradiation. “This study provides suggestive evidence that skin-derived NO metabolites may have a role in modulation of blood pressure upon UV exposure,” Thomas Michel, a professor of medicine and biochemistry at Harvard Medical School. Reference: Donald Liu, Bernadette O Fernandez, Alistair Hamilton, Ninian N Lang, Julie M C Gallagher, David E Newby, Martin Feelisch and Richard B Weller, UVA Irradiation of Human Skin Vasodilates Arterial Vasculature and Lowers Blood Pressure Independently of Nitric Oxide Synthase, Journal of Investigative Dermatology 20 February 2014 The information on this website is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge and information from the research and experience of Dr. Grisanti and his functional medicine community. Dr. Grisanti encourages you to make your own health care decisions based upon your research and in partnership with a qualified health care professional. Ronald Grisanti D.C., D.A.B.C.O., D.A.C.B.N., M.S., CFMP
An athletic 20 year man is playing basketball and suddenly collapses on the court and dies. On a hot July day, a young and vibrant college football player suddenly makes a great tackle and never gets up.. only to be pronounced dead 5 minutes later. High School track runner dies after finishing second in a race. The sad truth is 1 out of 50,000 young adults will fall victim to Sudden Death. Most sudden deaths have been linked to a thickened, enlarged heart called hypertrophic cardiomyopathy (HCM), or by a condition that disturbs the rhythm of the heart called an arrhythmia. When one sweats, a significant amount of magnesium is lost. Magnesium is the most under-recognized electrolyte disorder in the U.S. Dr. Mildred Seelig, one of the country's leading authorities on magnesium suggests that 80%-90% of the population is deficient is magnesium It is beyond the extent of this article why the public is being denied the truth of the seriousness of magnesium deficiency and sudden death. The amount of medical research could fill a book, but it is unfortunately being ignored. According to Micheal A. Brodsky M.D., associate professor of medicine at the University of Medicine and the director of the Cardiac Arrhythmia Service at the University of California, mineral imbalances interfere with the heart's normal nerve function. While most athletes have been conditioned to drink a potassium rich drink after sweating, very few have been educated on the dangers of a magnesium deficiency. Dr. Brodsky states that arrhythmia therapy should focus on replenishing two key minerals: potassium and magnesium. Almost all physicians have known for some time just how vital potassium is for normal heartbeat. Magnesium is an entirely different story, however. According to Carla Sueta M.D., Ph.D., assistant professor of medicine and cardiology at the University of North Carolina at Chapel Hill School of Medicine "apparently, many doctors still don't realize how important a role this mineral can play in some heart patients. In fact, most never check the magnesium level. She has shown through her research that magnesium reduced the incidence of several types of ventricular arrhythmia by 53 to 76 percent. Magnesium deficiency can be induced by the very drugs meant to help heart problems. Some types of diuretics (water pills) cause the body to excrete both magnesium and potassium, as does digitalis. And magnesium deficiency is often at the bottom of what's called refractory potassium deficiency. The amount of magnesium in the body determines the amount of a particular enzyme that determines the amount of potassium in the body," he explains. So if you are magnesium-deficient, you may in turn be potassium-deficient, and no amount of potassium is going to correct this unless you are also getting enough magnesium. The Best Test To Determine Your Level of Magnesium Although most physicians rarely check this important mineral, the few that do usually rely on test called Serum Magnesium. Unfortunately, this test only measures approximately 1% of the magnesium in your body; a poor test at best. The "Gold Standard" and the most accurate test is the RBC Minerals or more commonly called Elemental Analysis in Packed Erythrocytes. This test examines the levels of eight minerals and seven toxic heavy metals. The erythrocyte is the red blood cell that floats in our serum to carry oxygen to our cells. The minerals this test analyzes from inside the red blood cell includes magnesium, manganese, molybdenum, potassium, selenium, vanadium and zinc. Another test which has proven to be extremely valuable in detecting magnesium deficiencies is called the Urine Magnesium Loading Test. In this test, the patient collects a 24-hour urine sample and the total magnesium is measured. The patient is then given a dose Magnesium Chloride 18% and another 24-hour urine specimen is collected. The magnesium is again measured. If the body retains more than a certain amount of magnesium, then it is concluded that the body is magnesium deficient. Common Symptoms of Magnesium Deficiency The most common symptoms include back and neck pain, muscle spasms, anxiety, panic disorders, Raynaud's spastic vessels, arrhythmia, fatigue, eye twitches, vertigo, migraines. Best Sources of Magnesium The best way of insuring enough magnesium is to eat a variety of whole foods, including whole grains, nuts, seeds and vegetables, preferably food grown on naturally composted soil. The green color of green vegetables is due to chlorophyll, which is a molecule that contains magnesium. Avoid refined processed foods, especially white sugar and white flour products, as most magnesium is removed from them. Here is an excellent form of magnesium I recommend NutriCology's Magnesium Chloride Liquid 8 fl oz Dr. Grisanti's Comments: If you are suffering with a heart problem and have not had your magnesium checked, then I want to urge you to have your physician order the two tests listed above. Unless you have proof that your magnesium is within normal levels, I want you to realize that you are playing with your health! <> References Eisenberg MJ, Magnesium deficiency and sudden death (editorial), AM Heart J 1992 Aug; 124(2):544-9 Magnes Res 1994 Jun;7(2):145-53 Tzivoni, Dan, M.D. and Keren, Andre, M.D., "Suppression of Ventricular Arrhythmias by Magnesium", The American Journal of Cardiology, June 1, 1990;65:1397-1399. Miner Electrolyte Metab 1993;19(4-5):323-36 Keller, Peter K. and Aronson, Ronald S., "The Role of Magnesium in Cardiac Arrhythmias", Progress in Cardiovascular Diseases, May/June 1990;32(6):433-448. Biochim Biophys Acta 1993 Oct 20;1182(3):329-32 Biochim Biophys Acta 1994 Jan 11;1225(2):158-64 Practical Briefings: Clinical News You Can Put Into Your Practice Now. Ventricular Arrhythmias and Magnesium", Patient Care, October 15, 1990;16-20 Magnes Res 1993 Jun;6(2):191-2 Hennekens (1987) Epidemiology Medicine, p.54-98 Schriftenr Ver Wasser Boden Lufthyg 1993;88:474-90 Am J Cardiol 1992 Oct 8;70(10):44C-49C Fiziol Zh SSSR Im I M Sechenova 1992 Jul;78(7):71-7 The information on this website is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge and information from the research and experience of Dr. Grisanti and his functional medicine community. Dr. Grisanti encourages you to make your own health care decisions based upon your research and in partnership with a qualified health care professional. Visit www.FunctionalMedicineUniversity.com for more information on our training in functional medicine. |
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